Coronvirus desies and its consequences have caused concern among various segments of society. In particular, the change in teaching methods from online to face-to-face training and the damage caused by this process in some cases has made this educational process difficult. Thus, identifying students' concerns and understanding the predictions of ANXIETY in the reopening of educational institutions will allow us to address the roots of this factor after the Corona epidemic and the reopening of schools.. This research is a qualitative research and content analysis and its statistical population is high school students in Tehran at the time of reopening of schools after the Corona epidemic. From this statistical population, 40 male and female subjects who met the research criteria were selected. After interviewing the subjects and analyzing them, sub-themes and main themes have been identified and classified.

Aims: DEATH is an important and significant issue in nursing. The present study aimed to explain DEATH ANXIETY among nursing students using a qualitative approach. Participants & Methods: The present qualitative study was conducted on 12 nursing students from the School of Nursing and Midwifery in Zahedan during 2023-2024. The participants were selected through purposive sampling and attended semi-structured interviews after providing informed consent. The interviews were immediately transcribed and analyzed using a conventional content analysis technique. The data were coded by MAXQDA2020 software and analyzed using the content analysis method proposed by Graneheim and Lundman. Findings: The students recognized the reality of DEATH and its existential necessity. They also pointed to the lack of confrontation with DEATH and after-DEATH experiences, the meaning of DEATH, the quality of DEATH and dying, concerns about survivors, and emotional confrontation. Conclusion: There are many concepts regarding the concept of DEATH, with one of the most important ones highlighted by almost all participants being the reality of DEATH and its existential necessity.

Background: Acute myeloid leukemia (AML) is clinically, cytogenetically, and molecularly heterogeneous. Advances in molecular research have greatly improved our understanding of the leukemogenesis in AML. Programmed cell DEATH-4 (PDCD4) is a novel tumor suppressor that inhibits neoplastic transformation and tumor progression and invasion by suppressing activator protein (AP) -1 activation and protein translation. In the present study, we examined the PDCD4 expression levels in de novo AML and investigated correlation between altered expression of PDCD4 with patients’ clinical characteristics.Methods: Peripheral blood samples were collected from 56 patients with AML at the time of diagnosis and also, 10 healthy individuals. Quantification of PDCD4 mRNA expression by Real Time Quantitative PCR was performed. Mann-Whitney U test was used to compare PDCD4 expression differences among healthy and AML samples.Findings: PDCD4 mRNA expression was significantly diminished in patients with AML at diagnosis in comparison to the PB as normal samples (P<0.001). We observed a statistically lower expression in AML-M5 subtype in comparison to other AML subtypes (P=0.028). We have not found any significant correlation between PDCD4 expression level and clinical parameters of patients. Also, no significant correlation between the expression levels of PDCD4 and complete remission after induction therapy was observed.Conclusion: Our results shown that, like many epithelial cancers, the down-regulation of PDCD4 expression also occurs in AML.

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